Preparation and Characterization of Electrospun Chitosan/Poly(Vi

Preparation and Characterization of Electrospun Chitosan/Poly(Vinyl alcohol) as Tissue Engineering Platform
F. Mottaghitalab, M. Shokrgozar, N. Amiralyan, A. Eslamifar , V. Mottaghitalab

Abstract
As the field of tissue engineering advances, new tools for better monitoring and evaluating of engineered tissue along with new biomaterials to direct tissue growth are needed. Tissue regenerations are achieved with the aid of polymeric scaffolds which serves as matrixes for cellular in-growth, proliferation and new tissue formation in three-dimensions. Electrospinning is a most effective method to fabricate polymer scaffolds. These scaffolds have the ability to form a nano-sized fibrous structure with interconnected pores mimicking the extracellular matrix (ECM) for tissue formation. In the present study, chitosan/poly(vinyl alcohol) blends have been exploited as scaffold. The morphology of nanofibers, and viability of cultured cells were characterized.
Key words: Tissue engineering, Scaffold, Electrospinning, Chitosan, PVA

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مدیر سایت چهارشنبه 4 اردیبهشت‌ماه سال 1392 ساعت 06:41 ق.ظ